Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD
Sorghum Extract
MODERATE EVIDENCESupplementLast updated
AVELOR SUMMARY
Dynamine® (methylliberine) from sorghum is a purine alkaloid structurally similar to caffeine and theacrine but with FASTER onset and SHORTER duration — 'the espresso shot of nootropics.' Acts on adenosine and dopamine receptors. Does NOT increase BP or HR in preliminary data. Onset: 15-30 minutes. Duration: 1-3 hours (vs caffeine's 5-6 hours). Dose: 100-200mg. No tolerance development reported. Often stacked with TeaCrine® for extended duration.
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*Reviewed by the Dose AI Research Team and Clinical Advisory Board*
*Last updated: 2026-04-06*
Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:
Not medical advice. Based on published clinical research and systematic reviews.