Is Shark Cartilage safe to take daily?

Shark Cartilage is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Shark Cartilage

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Shark cartilage was marketed as an anti-cancer supplement based on the premise that 'sharks don't get cancer' — which is FALSE (sharks DO get cancer, including cartilage cancer). The anti-angiogenic theory was plausible but multiple clinical trials found NO benefit for cancer. A 2005 Mayo Clinic RCT and a 2010 NCI Phase III trial both found shark cartilage was ineffective for non-small-cell lung cancer. Also: overfishing concern (shark populations declining). Our assessment: DEBUNKED. Sharks get cancer. Shark cartilage doesn't treat it. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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