What is the recommended dose of Olive Leaf Extract?

- **Look for:** Standardized to 15-20% oleuropein; Benolea brand (most clinical data); or specify hydroxytyrosol content; 500mg+ per serving - **Avoid:** Unstandardized olive leaf powder or tea; pr...

Is Olive Leaf Extract safe to take daily?

Olive Leaf Extract is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

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Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Olive Leaf Extract

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Olive leaf extract is rich in oleuropein and hydroxytyrosol — polyphenols from the Mediterranean diet with evidence for blood pressure reduction, blood sugar management, and cardiovascular protection. Our research shows a 2017 RCT where olive leaf extract (500mg/day) reduced blood pressure by 11.5/4.8 mmHg over 8 weeks — comparable to captopril (ACE inhibitor). The European Food Safety Authority (EFSA) authorized a health claim for hydroxytyrosol's protection against LDL oxidation. This is one of the more evidence-backed herbal supplements for cardiovascular health.

WHAT IT DOES

Oleuropein and its metabolite hydroxytyrosol work through: (1) ACE inhibition — reducing angiotensin II production, lowering blood pressure through the same mechanism as captopril; (2) calcium channel blocking — vasodilation; (3) potent antioxidant activity — hydroxytyrosol has an ORAC (antioxidant capacity) value higher than vitamin C, CoQ10, or resveratrol; (4) AMPK activation — improving insulin sensitivity and glucose uptake; (5) antimicrobial — direct disruption of bacterial cell membranes. The cardiovascular protection is multi-modal, which is consistent with the Mediterranean diet's well-documented heart benefits.

OPTIMAL DOSAGE

Look for: Standardized to 15-20% oleuropein; Benolea brand (most clinical data); or specify hydroxytyrosol content; 500mg+ per serving
Avoid: Unstandardized olive leaf powder or tea; products without polyphenol quantification
Minimum effective dose: 500mg/day standardized to 15% oleuropein
Third-party tested brands: Gaia Herbs, Nature's Way (Olive Leaf), Swanson (standardized to oleuropein)

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SAFETY PROFILE

Critical Interactions (Do Not Combine Without Medical Supervision)

Moderate Interactions (Monitor Closely)

Theoretical/Low-Risk Interactions

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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