Is Neem safe to take daily?

Neem is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Neem

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Neem is the Ayurvedic 'village pharmacy' — antimicrobial, antifungal, anti-diabetic, and contraceptive. Azadirachtin and nimbidin are the active compounds. Neem oil is contraceptive in both sexes (spermicidal + anti-implantation). Used as a biopesticide (neem oil is EPA-registered). Anti-diabetic evidence: reduced fasting glucose by 15-25% in small Indian studies. CAUTION: hepatotoxicity at high oral doses; contraindicated in pregnancy (abortifacient); contraindicated in children (Reye's syndrome-like reaction reported). Primarily used externally for skin/hair in Western markets. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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