What is the recommended dose of Cranberry?

- **Look for:** Standardized to ≥36mg proanthocyanidins type A (PACs-A) per serving, measured by BL-DMAC method; Cran-Max or Ellura brands (most studied) - **Avoid:** Cranberry juice cocktails (hig...

Is Cranberry safe to take daily?

Cranberry is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

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Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Cranberry

MODERATE EVIDENCESupplementLast updated

AVELOR SUMMARY

Cranberry's primary clinically validated use is preventing recurrent urinary tract infections (UTIs) — a 2023 Cochrane meta-analysis of 50 RCTs confirmed it reduces UTI risk by 26% overall and by 53% in women with recurrent UTIs. The active compounds (proanthocyanidins type A, PACs-A) prevent E. coli from adhering to the bladder wall. Our research emphasizes that dose matters: products must deliver ≥36mg PACs-A per day to be effective, and many products fall short.

WHAT IT DOES

Cranberry's proanthocyanidins type A (PACs-A) have a unique A-type linkage that physically prevents E. coli fimbriae (the bacterial appendages that grip bladder cells) from attaching to the uroepithelium. Without attachment, bacteria are flushed out during urination. This is a mechanical anti-adhesion effect, not antimicrobial — cranberry doesn't kill bacteria, it prevents them from colonizing. The same anti-adhesion mechanism applies to H. pylori in the stomach and oral bacteria on teeth.

OPTIMAL DOSAGE

Look for: Standardized to ≥36mg proanthocyanidins type A (PACs-A) per serving, measured by BL-DMAC method; Cran-Max or Ellura brands (most studied)
Avoid: Cranberry juice cocktails (high sugar, low PACs); products standardized by weight only without PAC quantification; "cranberry extract 500mg" without PAC disclosure
Minimum effective dose: 36mg PACs-A per day
Third-party tested brands: Ellura (most clinical data for UTI), Cran-Max, Nature's Way (CranRich)

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SAFETY PROFILE

Critical Interactions (Do Not Combine Without Medical Supervision)

No critical interactions identified at standard supplement doses.

Moderate Interactions (Monitor Closely)

Theoretical/Low-Risk Interactions

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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