Is Vitamin K2 safe to take daily?

Vitamin K2 is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Vitamin K2

MODERATE EVIDENCEVitaminLast updated

AVELOR SUMMARY

Vitamin K2 (MK-4 and MK-7) activates osteocalcin (bone) and matrix-Gla protein (anti-vascular calcification). MK-7 has a 72-hour half-life (vs MK-4's 1-2 hours) — one daily dose maintains steady levels. The Rotterdam Study: highest K2 intake → 50% reduction in arterial calcification, 50% reduction in cardiovascular death. 90-200μg/day MK-7. MenaQ7® is the gold-standard branded MK-7 with the most clinical data. for the synergistic combination. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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