Is Vitamin B1 safe to take daily?

Vitamin B1 is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Vitamin B1

MODERATE EVIDENCEVitaminLast updated

AVELOR SUMMARY

Thiamine is essential for pyruvate dehydrogenase (glucose metabolism) and transketolase (pentose phosphate pathway). Deficiency causes beriberi (wet/dry) and Wernicke-Korsakoff syndrome (alcoholism). High-dose thiamine (100-300mg/day) improved fatigue in IBD patients. Allithiamine and benfotiamine are fat-soluble forms with better absorption. Metformin, loop diuretics, and chronic alcohol deplete thiamine. RDA: 1.1-1.2mg/day. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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