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Gut Health & Digestion: Evidence-Based Supplement Guide

What works, what does not, and what is dangerous. Reviewed by the Scan Dose Research Team.

12 supplements reviewedPubMed citedDrug interactions checked

What Works (Evidence-Based)

SupplementGrade Evidence

Effective Dose

Key Finding

Probiotics (strain-specific)Grade A

Varies by strain

ONLY specific strains for specific conditions. Random blends = no evidence.

Psyllium fiberGrade A

5-10g/day with water

Most-proven fiber. Also modestly lowers cholesterol.

Peppermint oil (enteric-coated)Grade B

180-225mg before meals

Reduces IBS symptoms. Must be enteric-coated.

GingerGrade B

250mg-1g

Pregnancy nausea, chemo nausea, motion sickness.

Lactase enzymeGrade A

With dairy meals

Only digestive enzyme with strong evidence.

What Does Not Work (Save Your Money)

Supplement

Finding

"Gut cleanse" supplements

Zero evidence. Liver and kidneys handle detox.

Digestive enzyme blends

No benefit without diagnosed deficiency

Collagen for gut healing

No clinical evidence for "leaky gut"

Bone broth for gut

No evidence. Contains lead (0.7-9.5 mcg/L).

Aloe vera for IBS

No reliable evidence

Related Ingredients

Probiotics (strain-specific)Grade A

Psyllium fiberGrade A

Peppermint oil (enteric-coated)Grade B

Reviewed by the Scan Dose Research Team and Clinical Advisory Board

These statements have not been evaluated by the FDA. This content is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any supplement regimen.

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