Is Ruscus aculeatus safe to take daily?

Ruscus aculeatus is rated "Generally Safe" based on clinical evidence. Always consult your healthcare provider before starting any supplement.

Ingredient Research

Graded against 173,636 supplements + 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, NIH DSLD

Ruscus aculeatus

MODERATE EVIDENCEBotanicalLast updated

AVELOR SUMMARY

Butcher's broom is a European herb for chronic venous insufficiency. Ruscogenins (steroidal saponins) activate alpha-1 adrenergic receptors on venous smooth muscle — CONSTRICTING veins to improve venous return. A 2002 meta-analysis found it significantly reduced CVI symptoms. Dose: 300-450mg/day standardized to 7-11mg ruscogenins. Often combined with hesperidin and vitamin C. Fagorutin® and Ruscovar® are branded extracts. --- *Reviewed by the Dose AI Research Team and Clinical Advisory Board* *Last updated: 2026-04-06*

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Independently graded against 173,636 indexed supplements with 177 published clinical interactions, sourced from PubMed, FDA CAERS, openFDA, and NIH DSLD | Last updated:

Not medical advice. Based on published clinical research and systematic reviews.

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